代表性论文
1. You, H., Rideau, E., Sidera, M. & Fletcher, S. P. Non-stabilized nucleophiles in Cu-catalysed dynamic kinetic asymmetric allylic alkylation. Nature. 517, 351–355 (2015).DOI: 10.1038/nature14089
2. Rideau, E., You, H., Sidera, M., Claridge, T. D. W. & Fletcher, S. P. Mechanistic studies on a Cu-catalyzed asymmetric allylic alkylation with cyclic racemic starting materials. J. Am. Chem. Soc. 139, 5614–5624 (2017).DOI: 10.1021/jacs.7b02440
3. Wang, J.,Li, J., Wang, Y., He, S., You, H. & Chen, F. Polymer-Supported Chiral Heterogeneous Copper Catalyst for Asymmetric Conjugate Addition of Ketones and Imines under Batch and Flow. ACS Catal. 9629–9637 (2022). DOI: 10.1021/acscatal.2c02056
4. Jun Li, Xiao Song, Yan Wang, Junrong Huang, Hengzhi You and Fen-Er Chen. Copper-Catalyzed Asymmetric Allylic Alkylation of Racemic Inert Cyclic Allylic Ethers under Batch and Flow. Chemical Science, 2023, 14, 4351–4356, DOI: 10.1039/D3SC00127J
5. Chao Wang, Yan Wang, Xuelei Jia, Junrong Huang, Hengzhi You, Fen-Er Chen. Recyclable Silica-Support Taniaphos/Copper(Ⅰ) complex for asymmetric allylic alkylation reactions, Journal of Catalysis, 2023, 425, 50-56, DOI: https://doi.org/10.1016/j.jcat.2023.05.025
6. Ana Xu; Chaoyi Li; Junrong Huang; Heng Pang; Chengyao Zhao; Lijuan Song; Hengzhi You; Xumu Zhang; Fen-Er Chen. Highly enantioselective synthesis of both tetrahydroquinoxalines and dihydroquinoxalinones via Rh–thiourea catalyzed asymmetric hydrogenation. Chemical Science, 2023, 14, 9024–9032, DOI: 10.1039/D3SC00803G
7. Jiaping Yu+; Jiaying Liu+; Chaoyi Li; Junrong Huang; Yuxiang Zhu; Hengzhi You;Recent advances and applications in high-throughput continuous flow; Chemical Communications, 2024, 60, 3217–3225; DOI:10.1039/D3CC06180A
8. Jun Li+; Junrong Huang+; Yan Wang; Yuexin Liu; Yuxiang Zhu; Hengzhi You; Fen-Er Chen. Copper-Catalyzed Asymmetric Allylic Substitution of Racemic/meso Substrates.Chemical Science, 2024, 15, 8280 - 8294, DOI: 10.1039/D4SC02135E
9. Junwen Wang; Feng Liang; Junrong Huang; Jun Li; Jingyuan Liao; Chengyao Zhao; Hengzhi You; Tao Tu; Fen-Er Chen. Amplifying enantioselectivity in asymmetric transformations using heterogeneous chiral single-rhodium-site catalyst with sustained catalytic activity. Chemical Engineering Journal, 2024-07, DOI: 10.1016/j.cej.2024.152387
10. Jun Li; Yu Wang; Yan Wang; Lianjie Zhai; Junrong Huang; Lijuan Song; Hengzhi You; Desymmetrization of Inert meso-Diethers through Copper-Catalyzed Asymmetric Allylic Alkylation with Grignard Reagents. Organic Letters, 2024, 26, 27, 5844–5849, DOI: 10.1021/acs.orglett.4c01972
11. Ana Xu; Lanxing Ren; Junrong Huang; Yuxiang Zhu; Gang Wang; Chaoyi Li; Yongqiang Sun; Lijuan Song; Hengzhi You; Fen-Er Chen. Highly enantioselective synthesis of both enantiomers of tetrahydroquinoxaline derivatives via Ir-catalyzed asymmetric hydrogenation. Chemical Science, 2024, 15, 15243 - 15254; DOI: 10.1039/D4SC04222K
12. Junwen Wang; Feng Liang; Zhen Dong; Junrong Huang; Yuxiang Zhu; Hengzhi You; Fen-Er Chen. Four-step continuous-flow total synthesis of (-)-debromoflustramine B using a chiral heterogeneous Pd NP catalyst. Chemical Science, 2024 | Journal article; DOI: 10.1039/D4SC03471F
13. Jingyuan Liao; Renrong Zhang; Xuelei Jia; Meiling Wang; Chaoyi Li; Juntao Wang; Renjin Tang; Junrong Huang; Hengzhi You; Fen-Er Chen. Green solvent mixture for ultrasound-assisted solid-phase peptide synthesis: a fast and versatile method and its applications in flow and natural product synthesis. Green Chemistry, 2024, 26, 10549 - 10557; DOI: 10.1039/D4GC03864A
2025年发表论文(通讯作者)
44. Rashed Rahman; Fazal Malik; Zaw Min Hein; Junrong Huang; Hengzhi You; Yuxiang Zhu,Continuous Flow Synthesis and Applications of Metal‐Organic Frameworks: Advances and Innovations, ChemPlusChem, 2025-01-03 | Journal article, DOI: 10.1002/cplu.202400634
43. Dongxuan He; Gang Wang; Binghan Li; Junrong Huang; Shuming Dou; Wei Gan; Hengzhi You; Qunhui Yuan,Ultrafast fabrication of Pd/C as a highly active and stable heterogeneous catalyst for hydrogenation synthesis of tris(hydroxymethyl)aminomethane under batch and flow, Surfaces and Interfaces, 2025-01 | Journal article, DOI: 10.1016/j.surfin.2024.105721
2024年发表论文(通讯作者)
42. Chaoyi Li, Minghao Su, Tianyi Hou, Yuhe Shi, Junrong Huang, Jing Qing, Wenxin Niu, Yinghe Zhang, Ling zhang, and Hengzhi You, Two new amino acid derivatives as green corrosion inhibitors against Q235 steel in HCl solution: Experimental and theoretical investigations, Int. J. Miner. Metall. Mater.,(2024). DOI: https://dx.doi.org/10.1007/s12613-024-3011-8
41. Jingyuan Liao; Renrong Zhang; Xuelei Jia; Meiling Wang; Chaoyi Li; Juntao Wang; Renjin Tang; Junrong Huang; Hengzhi You; Fen-Er Chen. Green solvent mixture for ultrasound-assisted solid-phase peptide synthesis: a fast and versatile method and its applications in flow and natural product synthesis. Green Chemistry, 2024, 26, 10549 - 10557; DOI: 10.1039/D4GC03864A
40. Junwen Wang; Feng Liang; Zhen Dong; Junrong Huang; Yuxiang Zhu; Hengzhi You; Fen-Er Chen. Four-step continuous-flow total synthesis of (-)-debromoflustramine B using a chiral heterogeneous Pd NP catalyst. Chemical Science, 2024 | Journal article; DOI: 10.1039/D4SC03471F
39. Ana Xu; Lanxing Ren; Junrong Huang; Yuxiang Zhu; Gang Wang; Chaoyi Li; Yongqiang Sun; Lijuan Song; Hengzhi You; Fen-Er Chen. Highly enantioselective synthesis of both enantiomers of tetrahydroquinoxaline derivatives via Ir-catalyzed asymmetric hydrogenation. Chemical Science, 2024, 15, 15243 - 15254;DOI: 10.1039/D4SC04222K
38. Xiaowen Zhang; Yang Li; Chaoyi Li; Jingyuan Zhu; Zhiqiang Gan; Lei Wang; Xiaofei Sun; Hengzhi You; A chemical reaction entity recognition method based on a natural language data augmentation strategy. Chemical Communications, 2024, 60, 9610 - 9613; DOI: 10.1039/D4CC01471E
37. Jun Li; Yu Wang; Yan Wang; Lianjie Zhai; Junrong Huang; Lijuan Song; Hengzhi You; Desymmetrization of Inert meso-Diethers through Copper-Catalyzed Asymmetric Allylic Alkylation with Grignard Reagents. Organic Letters, 2024, 26, 27, 5844–5849, DOI: 10.1021/acs.orglett.4c01972
36. Junwen Wang; Feng Liang; Junrong Huang; Jun Li; Jingyuan Liao; Chengyao Zhao; Hengzhi You; Tao Tu; Fen-Er Chen. Amplifying enantioselectivity in asymmetric transformations using heterogeneous chiral single-rhodium-site catalyst with sustained catalytic activity. Chemical Engineering Journal, 2024-07, DOI: 10.1016/j.cej.2024.152387
35. Jun Li+; Junrong Huang+; Yan Wang; Yuexin Liu; Yuxiang Zhu; Hengzhi You; Fen-Er Chen. Copper-Catalyzed Asymmetric Allylic Substitution ofRacemic/meso Substrates. Chemical Science, 2024, 15, 8280 - 8294, DOI: 10.1039/D4SC02135E
34. Jiaping Yu+; Jiaying Liu+; Chaoyi Li; Junrong Huang; Yuxiang Zhu; Hengzhi You;Recent advances and applications in high-throughput continuous flow; Chemical Communications, 2024, 60, 3217–3225; DOI:10.1039/D3CC06180A
33. 关东, 董珍, 陈凯, 李国威, 廖竞远, 黄均荣, 游恒志. L-10BPA中间体合成工艺优化及连续流可行性工艺研究 [J]. 当代化工研究 ,2023, (21):143-145.
32. Heng Pang+; Junrong Huang+; Juntao Wang; Gang Wang; Ana Xu; Lei Luo; Qunhui Yuan; Hengzhi You; Fen-Er Chen. Practical synthesis of tetrahydrofolate by highly efficient catalytic hydrogenation in continuous flow. Journal of Flow Chemistry (2024), DOI:10.1007/s41981-024-00310-7
2023年发表论文(通讯作者)
31. Ana Xu; Chaoyi Li; Junrong Huang; Heng Pang; Chengyao Zhao; Lijuan Song; Hengzhi You; Xumu Zhang; Fen-Er Chen. Highly enantioselective synthesis of both tetrahydroquinoxalines and dihydroquinoxalinones via Rh–thiourea catalyzed asymmetric hydrogenation. Chemical Science, 2023, 14, 9024 - 9032, DOI: 10.1039/D3SC00803G
30. Lei Xu, Gang Wang, Nianxin Rong, Yang Gu, Le’an Hu, Hengzhi You and Qin Yin. Enantioselective and Step-Economic Synthesis of the Chiral Amine Fragment in the Tyrosine Kinase Inhibitor Repotrectinib by Direct Asymmetric Reductive Amination under Batch and Flow, Org. Process Res. Dev., 2023, DOI: 10.1021/acs.oprd.3c00152
29. Xiao Song, Jing Qing, Jun Li, Xuelei Jia, Fusong Wu, Junrong Huang, Jian Jin, Hengzhi You. Copper-catalyzed asymmetric allyl alkylation using Grignard reagents under flow, Chinese Journal of Organic Chemistry, 2023, DOI: 10.6023/cjoc202303027.
28. Chao Wang, Yan Wang, Xuelei Jia, Junrong Huang, Hengzhi You, Fen-Er Chen. Recyclable Silica-Support Taniaphos/Copper(Ⅰ) complex for asymmetric allylic alkylation reactions, Journal of Catalysis, 2023, 425, 50-56, DOI: https://doi.org/10.1016/j.jcat.2023.05.025
27. 卿晶,廖竞远,陈凯,代德胜,游恒志. 13C-尿素的合成工艺优化及连续流工艺研究 [J].当代化工研究,2023,(08):146-148.
26. Jun Li, Xiao Song, Yan Wang, Junrong Huang, Hengzhi You and Fen-Er Chen. Copper-Catalyzed Asymmetric Allylic Alkylation of Racemic Inert Cyclic Allylic Ethers under Batch and Flow. Chemical Science, 2023, 14, 4351–4356, DOI: 10.1039/D3SC00127J
2022年发表论文(通讯作者)
25. Jingyuan Liao; Xuelei Jia; Fusong Wu; Junrong Huang; Guifu Shen; Hengzhi You; Fen-Er Chen. Rapid mild macrocyclization of depsipeptides under continuous flow: total syntheses of five cyclodepsipeptides. Org. Chem. Front., 2022, Advance Article, DOI: 10.1039/D2QO01577C
24. Dongliang Zhang, Fusong Wu, Zhijian Wan, Yichun Wang, Xuan He, Bing Guo, Hengzhi You and Fen-Er Chen. Palladium Polyaniline Complex: A Simple and Efficient Catalyst for Batch and Flow Suzuki-Miyaura Cross-couplings. Chemical Communications, 2022, DOI: 10.1039/D2CC04051D
23. Jun Li, Xiao Song, Fusong Wu, Hengzhi You, and Fen-Er Chen. Cu-Catalyzed Asymmetric Allylic Alkylation of Racemic CyclicAllyl Bromides with Organolithium Compounds. Eur. J. Org. Chem.2022, e202200860;DOI: 10.1002/ejoc.202200860
22. Wang, J.,Li, J., Wang, Y., He, S., You, H. & Chen, F. Polymer-Supported Chiral Heterogeneous Copper Catalyst for Asymmetric Conjugate Addition of Ketones and Imines under Batch and Flow. ACS Catal. 9629–9637 (2022). DOI: 10.1021/acscatal.2c02056
21. Xiaofei Sun,Jingyuan Zhu,Bin Chen ,Hengzhi You ,Huiqing Xu;A feature transferring workflow between data-poor compounds in various tasks;Pols one; 202204;DOI: 10.1371/journal.pone.0266088
20. Sun Xiaofei, Zhu Jingyuan, Chen Bin, You Hengzhi;融合多模态数据的药物合成反应的虚拟筛选;计算机应用;2022;DOI: 10.11772/j.issn.1001-9081.2021122228
2022年以前发表论文及非通讯作者论文
19. Xiqi Li, Aijie Wang, Zhe Yu, Hualin Wang, Hengzhi You, Jifei Xu, Jingyu Zhang, Wenzong Liu; New understanding of microbial growth cycle for efficient waste-activated sludge disposal by preserving microbial self-degradation activity during the decline phase, Water Research X, Volume 27, 2025,100323, ISSN 2589-9147, https://doi.org/10.1016/j.wroa.2025.100323.
18. Mingxing Nie; Zhengyu Xu; Yu Wang; Hengzhi You; Lei Luo; Binghan Li; Sadaf Mutahir; Wei Gan; Qunhui Yuan; Ultrafast synthesis of efficient TS-PtCoCu/CNTs composite with high feed-to-product conversion rate by Joule heating for electrocatalytic oxidation of ethanol; Journal of Colloid and Interface Science; 2024-04;DOI: 10.1016/j.jcis.2024.01.090
17. Yufeng Xie; Huaying Liu; Zhong-Liang Li; Xin Zhang; Lijuan Song; Kang Zhou; Feng Yuan; Hengzhi You; Engui Zhao; Zikai He; Construction of chiral through-space luminophores via symmetry breaking triggered by sequenced chlorination; Science China Chemistry; 202305 ;DOI: 10.21203/rs.3.rs-2258314/v1
16. Jingyuan Liao, Shilong Zhang, Zesheng Wang, Xiao Song, Dongliang Zhang, Ravi Kumar, Jian Jin, Peng Ren, Hengzhi You, Fen-Er Chen;Transition-metal catalyzed asymmetric reactions under continuous flow from 2015 to early 2020;Green Synthesis and Catalysis;202008;DOI: 10.1016/j.gresc.2020.08.001
15. Brij Mohan; Zhiyu Tao; Sandeep Kumar; Tiantian Xing; Shixuan Ma; Wenbin Huang; Xueping Yang; Hengzhi You; Peng Ren; Water- and pH-Stable Methylthio-Containing Metal–Organic Frameworks as Luminescent Sensors for Metal-Ion Detection; Crystal Growth & Design; 2022; DOI: 10.1021/acs.cgd.2c00493
14. Mohan, B.,Kumar, S.,Xi, H.,Ma, S.,Tao, Z.,Xing, T.,You, H.,Zhang, Y.,Ren, P; Fabricated Metal-Organic Frameworks (MOFs) as luminescent and electrochemical biosensors for cancer biomarkers detection; Biosensors and Bioelectronics; 2022; DOI: 10.1016/j.bios.2021.113738
13. Mohan, B.,Modi, K.,Parikh, J.,Ma, S.,Kumar, S.,Kumar Manar, K.,Sun, F.,You, H.,Ren, P; Efficacy of 2-nitrobenzylidene-hydrazine-based selective and rapid sensor for Cu2 ions, histidine, and tyrosine: Spectral and computational stud; Journal of Photochemistry and Photobiology A: Chemistry; 2022; DOI: 10.1016/j.jphotochem.2021.113557
12. Kumar, S.,Mohan, B.,Tao, Z.,You, H.,Ren, P; Incorporation of homogeneous organometallic catalysts into metal-organic frameworks for advanced heterogenization: A review; Catalysis Science and Technology; 2021; DOI: 10.1039/d1cy00663k
11. Wan, Z.,Tao, Y.,You, H.,Zhang, X.,Shao, J; Na-ZSM-5 Zeolite Nanocrystals Supported Nickel Nanoparticles for Efficient Hydrogen Production from Ammonia Decomposition; ChemCatChem; 2021; DOI: 10.1002/cctc.202100324
10. Wan, Z.,Tao, Y.,You, H.,Shao, J; Facile synthesis of a sintering-resistant zeolite confined Ni catalyst for efficient COx-free hydrogen generation from ammonia decomposition; Sustainable Energy and Fuels; 2021; DOI: 10.1039/d1se00417d
9. Kumar, S.,Liu, S.,Mohan, B.,Zhang, M.,Tao, Z.,Wan, Z.,You, H.,Sun, F.,Li, M.,Ren, P; Fluorine-Containing Triazole-Decorated Silver(I)-Based Cationic Metal-Organic Framework for Separating Organic Dyes and Removing Oxoanions from Water; Inorganic Chemistry; 2021; DOI: 10.1021/acs.inorgchem.0c03688
8. Mohan, B.,Kumar, S.,Ma, S.,You, H.,Ren, P; Mechanistic Insight into Charge and Energy Transfers of Luminescent Metal–Organic Frameworks Based Sensors for Toxic Chemicals; Advanced Sustainable Systems; 2021; DOI: 10.1002/adsu.202000293
7. Mohan, B.,Modi, K.,Patel, C.,Kumar, S.,Zhiyu, T.,You, H.,Ren, P; A new N-methylhydrazinecarbothioamide incorporated “naked-eye” and “turn-off” chemosensor for selective and low detection of Cu2 ions and computation study; Journal of Photochemistry and Photobiology A: Chemistry; 2021; DOI: 10.1016/j.jphotochem.2020.113097
6. Wan, Z.,Tao, Y.,Shao, J.,Zhang, Y.,You, H; Ammonia as an effective hydrogen carrier and a clean fuel for solid oxide fuel cells; Energy Conversion and Management; 2021;DOI: 10.1016/j.enconman.2020.113729
5. Liu, F.,Kumar, S.,Li, S.,You, H.,Ren, P.,Zhao, L; Bifunctional design of stable metal-organic framework bearing triazole–carboxylate mixed ligand: Highly efficient heterogeneous catalyst for knoevenagel condensation reaction under mild conditions; Catalysis Communications; 2020; DOI: 10.1016/j.catcom.2020.106032
4. Rideau, E., You, H., Sidera, M., Claridge, T. D. W. & Fletcher, S. P. Mechanistic studies on a Cu-catalyzed asymmetric allylic alkylation with cyclic racemic starting materials. J. Am. Chem. Soc. 139, 5614–5624 (2017).DOI: 10.1021/jacs.7b02440
3. You, H., Rideau, E., Sidera, M. & Fletcher, S. P. Non-stabilized nucleophiles in Cu-catalysed dynamic kinetic asymmetric allylic alkylation. Nature. 517, 351–355 (2015).DOI: 10.1038/nature14089
2. Dai, Y.,Wu, F.,Zang, Z.,You, H.,Gong, H.;Ni-catalyzed reductive allylation of unactivated alkyl halides with allylic carbonates;Chemistry - A European Journal;2012;DOI: 10.1002/chem.201102984
1. Yin, H.,Zhao, C.,You, H.,Lin, K.,Gong, H.; Mild ketone formation via Ni-catalyzed reductive coupling of unactivated alkyl halides with acid anhydrides; Chemical Communications; 2012;DOI: 10.1039/c2cc33232a