教学科研系列

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基本信息

地址: G栋
邮箱: zhangyang07@hit.edu.cn

研究方向

My research interest combines computational and experimental approaches for pathogen and cancer research. On the computational side, my group is both developing and applying the latest deep learning technologies to analyze a wide range of biological and biochemical data, including (i) developing Artificial Intelligence (AI)-powered smart microscopic imaging to accelerate disease diagnostic and drug discovery. (ii) enabling deep learning techniques to be applied to omics data, (e.g. modeling of proteins, DNAs, miRNAs, LncRNAs, and mRNAs and their interactions, structures and/or dynamics in molecular, cellular and tissue level), for the discovery of novel diagnostic biomarkers and therapeutic targets. (iii) the use of deep learning in cheminformatics and chemical biology in guiding drug discovery to target those therapeutic targets and fight against disease. On the experimental side, my group combines imaging, high-throughput sequencing, mass spectrometry, and chemical biology to mechanistically understand diseases at the molecular level by addressing the fundamental question of how those molecules shape the disease systematically.

研究经历

2011/09-2012/03 香港大学李嘉诚医学院/University of Hong Kong,Research Assistant

2015/09-2020/12 哈尔滨工业大学(深圳)/Harbin Institute of Technology (Shenzhen), Assistant Professor

2021/01-Present 哈尔滨工业大学(深圳)/Harbin Institute of Technology (Shenzhen), Associate Professor

2024/07- 东京大学/ University of Tokyo, Japan, Visiting Professor


Associate editor: BMC Biology; Frontiers in Microbiology

Academic editor: PLOS Genetics

Editorial Board Member: Communications Biology

Guest editor: Trends in Analytical Chemistry. Special Issue: AI in analytical chemistry: from methodology to applications

学习经历

2009/09-2011/08 香港大学(University of Hong Kong),巴斯德研究中心(HKU-Pasteur Research Center),硕士(M.Phil.)

2012/04-2015/08 剑桥大学(University of Cambridge),病理系(Department of Pathology),博士(Ph.D.)

教学课程

现代生物学导论(本科生公共基础课) Introduction to Modern Biology

生物分析化学(研究生)Bioanalytical Chemistry

论文及基金


Publications


Details can be found at

https://orcid.org/0000-0002-3503-5161



Grants

  • 深圳市基础研究(自由探索)项目/Shenzhen Basic Research (Free Exploration) Project。

  • 深圳市高层次人才启动项目/Oversea Talent Startup Fund by Shenzhen City。

  • 中央高校基本科研业务费项目(哈尔滨工业大学科研创新基金)/Fundamental Research Funds for the Central Universities。

  • 广东省基础与应用基础研究基金, 省企联合基金-面上项目/Natural Science Foundation of Guangdong Province。

  • 广东省教育厅普通高校特色创新类项目/Project of Educational Commission of Guangdong Province of China。

  • 国家自然科学基金面上项目/National Natural Science Foundation of China。

  • 中国科学院基础医学与肿瘤研究所开放课题/Opening Project of Zhejiang Province Key Laboratory for Aptamer and Theranostics, The Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences。

  • 深圳市稳定支持面上项目/Shenzhen Stable Support Grant。

  • 英国皇家化学会研究合作基金/Royal Society of Chemistry Researcher Collaborations Grant。

  • 国家留学基金委访问学者/ China Scholarship Council。